Do I need to make a different CV for every job I apply for?

Almost certainly. Even if you’re applying for exactly the same position with a variety of different employers, the differences between the employers themselves make it worthwhile tweaking your basic CV template to a greater or lesser extent in order to make it appeal to each one individually. Most jobseekers, whatever their industry and level, tend to apply for a range of different jobs, each with its own different core requirements and emphasis, and it’s always worth producing a fresh CV with the specific needs of that job and organisation in mind.